Geneab P16Ink4A

p16INK4A

E8ET1608-62 100ul
EUR 275
Description: Available in various conjugation types.

Genomeme Laboratories manufactures the geneab p16ink4a reagents distributed by Genprice. The Geneab P16Ink4A reagent is RUO (Research Use Only) to test human serum or cell culture lab samples. To purchase these products, for the MSDS, Data Sheet, protocol, storage conditions/temperature or for the concentration, please contact Genomeme. Other Geneab products are available in stock. Specificity: Geneab Category: P16Ink4A

True Blue

1mg Ask for price
  • SMILES: N=C(C1=CC=C(OC(/C=C/C2=CC3=CC(C(N)=N)=CC=C3O2)=C4)C4=C1)N.Cl.Cl
  • Formula: C20H18Cl2N4O2
Description: True Blue

True Blue

50mg Ask for price
  • SMILES: N=C(C1=CC=C(OC(/C=C/C2=CC3=CC(C(N)=N)=CC=C3O2)=C4)C4=C1)N.Cl.Cl
  • Formula: C20H18Cl2N4O2
Description: True Blue

True Blue

5mg Ask for price
  • SMILES: N=C(C1=CC=C(OC(/C=C/C2=CC3=CC(C(N)=N)=CC=C3O2)=C4)C4=C1)N.Cl.Cl
  • Formula: C20H18Cl2N4O2
Description: True Blue

p16INK4A Antibody

100ul
EUR 499

p16INK4A Antibody

100ul
EUR 399.6

p16INK4A Antibody

50ul
EUR 286.8

CDKN2A/p16INK4a

100ul
EUR 275
Description: Available in various conjugation types.

Test Assays information

P16INK4a Antibody

R35748-100UG 100 ug
EUR 339.15
  • 0.5 mg/ml in 1X TBS, pH7.3, with 0.5% BSA (US sourced) and 0.02% sodium azide
Description: Additional name(s) for this target protein: Cdkn2a, cyclin-dependent kinase inhibitor 2A, p19ARF; Cdkn2a

p16INK4a Antibody

abx026389-400l 400 µl
EUR 518.75

p16INK4a Antibody / CDKN2A

F54356-0.08ML 0.08 ml
EUR 140.25
  • In 1X PBS, pH 7.4, with 0.09% sodium azide
Description: This gene generates several transcript variants which differ in their first exons. At least three alternatively spliced variants encoding distinct proteins have been reported, two of which encode structurally related isoforms known to function as inhibitors of CDK4 kinase. The remaining transcript includes an alternate first exon located 20 Kb upstream of the remainder of the gene; this transcript contains an alternate open reading frame (ARF) that specifies a protein which is structurally unrelated to the products of the other variants. This ARF product functions as a stabilizer of the tumor suppressor protein p53 as it can interact with, and sequester, MDM1, a protein responsible for the degradation of p53. In spite of the structural and functional differences, the CDK inhibitor isoforms and the ARF product encoded by this gene, through the regulatory roles of CDK4 and p53 in cell cycle G1 progression, share a common functionality in cell cycle G1 control. This gene is frequently mutated or deleted in a wide variety of tumors, and is known to be an important tumor suppressor gene.

p16INK4a Antibody / CDKN2A

F54356-0.4ML 0.4 ml
EUR 322.15
  • In 1X PBS, pH 7.4, with 0.09% sodium azide
Description: This gene generates several transcript variants which differ in their first exons. At least three alternatively spliced variants encoding distinct proteins have been reported, two of which encode structurally related isoforms known to function as inhibitors of CDK4 kinase. The remaining transcript includes an alternate first exon located 20 Kb upstream of the remainder of the gene; this transcript contains an alternate open reading frame (ARF) that specifies a protein which is structurally unrelated to the products of the other variants. This ARF product functions as a stabilizer of the tumor suppressor protein p53 as it can interact with, and sequester, MDM1, a protein responsible for the degradation of p53. In spite of the structural and functional differences, the CDK inhibitor isoforms and the ARF product encoded by this gene, through the regulatory roles of CDK4 and p53 in cell cycle G1 progression, share a common functionality in cell cycle G1 control. This gene is frequently mutated or deleted in a wide variety of tumors, and is known to be an important tumor suppressor gene.

CDKN2A/p16INK4a Antibody

AF0228 200ul
EUR 420

CDKN2A/p16INK4a Antibody

AF5484 200ul
EUR 420

CDKN2A/p16INK4a Antibody

AF5484-100ul 100ul
EUR 280
  • Human,Mouse

CDKN2A/p16INK4a Antibody

AF5484-200ul 200ul
EUR 350
  • Human,Mouse

CDKN2A/p16INK4a Antibody

AF6898 100ul
EUR 420

CDKN2A/p16INK4a Antibody

AF6898-100ul 100ul
EUR 280
  • Human

CDKN2A/p16INK4a Antibody

AF6898-200ul 200ul
EUR 350
  • Human

CDKN2A/p16INK4a Antibody

AF6667 100ul
EUR 420

CDKN2A/p16INK4a Antibody

AF6667-100ul 100ul
EUR 280
  • Human

CDKN2A/p16INK4a Antibody

AF6667-200ul 200ul
EUR 350
  • Human

p16INK4a Antibody / CDKN2A

R20284-0.1ML 100ul
EUR 347.65
  • Antibody in PBS with 50% glycerol, 1% BSA and 0.09% sodium azide
Description: This recombinant p16INK4a antibody reacts to human p16INK4a (Cyclin-dependent kinase inhibitor 2A).

CDKN2A Antibody / p16INK4a

R20425-0.1ML 100ul
EUR 409

p16INK4a Antibody / CDKN2A

V8694-100UG 100 ug
EUR 424.15
  • 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide
Description: p16INK4a is a tumor suppressor protein. It is a specific inhibitor of cdk4/cdk6, and a tumor suppressor involved in the pathogenesis of a variety of malignancies. Recent analyses of the p16INK4a gene revealed homozygous deletions, nonsense, missense, or frameshift mutations in several human cancers. Although the frequency of p16INK4a abnormalities is higher in tumor derived cell lines than in unselected primary tumors, significant subsets of clinical cases with aberrant p16INK4a gene have been reported among melanomas, gliomas, esophageal, pancreatic, lung, and urinary bladder carcinomas, and some types of leukemia. Expression of p16INK4a (p16 positive) is highly correlated with human papilloma virus (HPV) infection in head and neck squamous cell carcinomas (HNSCC). p16 status is an important prognostic indicator in HNSCC and the p16 positive/HPV16 negative group is likely a distinct subgroup lacking any HPV genotype.